Question

What is malonate an enzyme inhibitor of?

1 year ago

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2 Replies

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Laurel Mann


2 Replies

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Dr. Maria Kamouyiaros Best Answer!

Malonate inhibits an enzyme involved in cellular respiration. Specifically malonate binds to the active site of the enzyme succinate dehydrogenase (competing with the succinate substrate of the enzyme) inhibiting its function.

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Aqeel A Best Answer!

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Malonate is a competitive inhibitor of the enzyme succinate dehydrogenase. It's shape is complementary to the active site of succinate dehydrogenase and hence competes with succinate (the substrate for succinate dehydrogenase).

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